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. 2020 Apr 30;7(12):2000871. doi: 10.1002/advs.202000871

Figure 10.

Figure 10

Models for mechanisms underlying MavC transglutamination and MvcA deubiquitination activities. A,B) UBE2N–Ub is produced by MavC via transglutamination (A, step 1 to step 2) and UBE2N–Ub is hydrolyzed to UBE2N and Ub by MvcA deubiquitination (B, step 1 to step 2) with rotation of their Insertion domains and Tail domains in directions indicated by gray arrows (step 2). Products release and the completion of the catalytic reactions (step 3).