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. 2020 Jun 5;21(11):4046. doi: 10.3390/ijms21114046

Figure 6.

Figure 6

Effects of sigma-1 receptor (σ1R) agonist and antagonist on the levels of interleukin-6 (IL-6). Abs. control (no treatment), 50% EtOH (50% ethanol enema), TNBS (2,4,6-trinitrobenzenesulfonic acid enema), FLV (TNBS enema + 1 mg/kg Fluvoxamine (FLV)), BD1063 (TNBS enema + 0.1 mg/kg BD1063), FLV + BD1063 (TNBS enema + 1 mg/kg FLV + 0.1 mg/kg BD1063). Data are represented as mean ± SEM; (n = 6–8); statistical significance ## p < 0.01 Abs. control vs. TNBS; ** p < 0.01 TNBS vs. TNBS + Treatment; && p < 0.01 EtOH vs. TNBS.