Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 27;21(11):3803. doi: 10.3390/ijms21113803

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Backbone RMSD distribution plots for PfProRS ligand-bound complexes. Conformational flexibility can be assessed by comparing the backbone RMSD distribution of each ligand-bound complex and the holo protein. Comparison of the mean (µ) of the holo protein (black dashed line) to each ligand complex (green dashed line) demonstrates the shift in conformation distribution of the complexes during the 200 ns MD simulation. σ is the standard deviation. (A) Holo system (PfProRS-ADN), (B) PfProRS-SANC152 complex, (C) PfProRS-SANC235 complex, (D) PfProRS-SANC236 complex, (E) PfProRS-SANC244 complex, (F) PfProRS-SANC318 complex, (G) PfProRS-SANC184 complex, (H) PfProRS-SANC257 complex, (I) PfProRS-SANC264 complex, (J) PfProRS-SANC456 complex and (K) PfProRS-SANC622 complex.