CD	Catalytic Domain
ABD	Anticodon Binding Domain
NTD	N-terminal Domain; MD, Molecular Dynamics
DRN	Dynamic Residue Network
RMSD	Root mean square deviation
RMSF	Root mean square fluctuation
SANCDB	South African Natural Compound Database
MSA	Multiple sequence alignment
AND	Adenosine
PCA	Principal component analysis
FEL	Free energy landscape
aaRS	aminoacyl tRNA synthetase
ProRS	Prolyl tRNA synthetase