Skip to main content
. 2020 May 27;21(11):3790. doi: 10.3390/ijms21113790

Figure 2.

Figure 2

Mechanisms regulating adipose stem cells expansion, including activation of target CCAAT/enhancer-binding proteins and PPARγ through recruitment of transcription factors including activators of transcription CREB, GR and STAT5, resulting in change of conformation of active sites on target proteins. Activated target CCAAT/enhancer-binding proteins regulate PPARγ through Sth40 mediated inhibition of C/EBPβ, while PPARγ itself stimulates expansion of adipose stem cells, by SWELL1/LRCC8 mediated activation of SWELL1 mediated VRAC signaling pathway. (Created with BioRender).