Figure 11.

RP11-838N2.3 knockdown could not affect the cell cycle of A549/DDP. (a) A549/DDP shRNA-NC. (b) A549/DDP shRNA. (c) A549/DDP shRNA-NC+2 μg/ml cisplatin. (d) A549/DDP shRNA+2 μg/ml cisplatin. (e) Compared with those in the A549/DDP shRNA-NC group, the cell ratios in the A549/DDP shRNA group in the G0/G1 phase (F = 1.012,P = 0.905), S phase (F = 0.341, P = 0.221), and G2/M phase (F = 1.942, P = 0.110) were not evidently different. Under the action of cisplatin, compared with those in the A549/DDP shRNA-NC+2 μg/ml cisplatin group, the cell ratios in the A549/DDP shRNA+2 μg/ml cisplatin group in the G0/G1 phase (F = 0.958, P = 0.400), S phase (F = 11.701, P = 0.662), and G2/M phase (F = 8.507, P = 0.248) were not different. There were also no significant differences in the proportion of cells.