Figure 13.

RP11-838N2.3 knockdown could affect the apoptosis of A549/DDP. (a) A549/DDP shRNA-NC. (b) A549/DDP shRNA. (c) A549/DDP shRNA-NC+2 μg/ml cisplatin. (d) A549/DDP shRNA+2 μg/ml cisplatin. (e) Compared with that of the A549/DDP shRNA-NC group, the apoptosis rate of the A549/DDP shRNA group was evidently increased (F = 5.828, P < 0.001). Under the action of cisplatin drugs, RP11-838N2.3 knockdown can also evidently promote the apoptosis of A549/DDP cells. Compared with that of the A549/DDP shRNA-NC+2 μg/ml cisplatin group, the apoptosis rate of the A549/DDP shRNA+2 μg/ml cisplatin group was also evidently increased (F = 3.322, P < 0.001). ∗∗∗P < 0.001.