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. 2020 Jun 14;2020:2806042. doi: 10.1155/2020/2806042

Figure 4.

Figure 4

Overexpression of RP11-838N2.3 could enhance proliferation efficiency of A549. (a) Compared with that of 0 h, the OD450mn of 24 h (P < 0.001, P < 0.001, P < 0.001, and P < 0.001), 48 h (P < 0.001, P < 0.001, P < 0.001, and P < 0.001), and 72 h (P < 0.001, P < 0.001, P < 0.001, P < 0.001, and P = 0.001) plainly increased. Compared with that of the A549 OE-NC group, the OD450mn of the A549 OE group increased significantly in 24 h (F = 0.406, P = 0.005), 48 h (F = 0.680, P = 0.001), and 72 h (F = 10.221, P = 0.04). (b) Under the action of 2 μg/ml cisplatin drug, RP11-838N2.3 overexpression still plainly promoted the proliferation of A549 cells. Compared with that of the A549 OE-NC+2 μg/ml cisplatin group, the OD450mn of A549 OE+2 μg/ml cisplatin group in 24 h (F < 0.001, P = 0.004), 48 h (F = 11.270, P = 0.015), and 72 h (F = 6.486, P = 0.033) all increased significantly. ∗P < 0.05; ∗∗P < 0.01.