Table 2.

Ratio of proliferative lymphatic vessels with LYVE-1 and proliferating cell nuclear antigen (PCNA) immunoreactivity (mean ± SE).

X-ray/ADSC	Day 0	Day 2	Day 8	Day 14
−/−	0.25 ± 0.07	0.15 ± 0.06	0.31 ± 0.06	0.45 ± 0.09
+/−	0.01 ± 0.01	0.24 ± 0.04 **	0.14 ± 0.06	0.27 ± 0.04 **
+/+	0.08 ± 0.03	0.26 ± 0.06 *	0.56 ± 0.05 **	0.61 ± 0.04 **

Proliferative lymphatic vessel ratio was calculated following the formula (n = 3–6): [(number of LYVE-1 and PCNA double-positive cells forming luminal structure)/(number of all LYVE-1 positive lumen)]. Four HPFs per mouse were selected. * p < 0.05, ** p < 0.01 significantly different from day 0.