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. 2020 Jun 8;21(11):4099. doi: 10.3390/ijms21114099

Figure 4.

Figure 4

SEMA3A-inhibitor attenuated Doxorubicin-induced c-Jun N-terminal kinase (JNK)/c-Jun signaling. Representative images of dual immunofluorescence staining of nephrin (green), p-c-Jun (red), and DAPI (blue) in glomeruli from the control, Dox, and Dox + SEMA3A-I groups at the time point of 2 weeks after Dox injection, showing the increased p-c-Jun-positive cells in glomeruli in the Dox group, while there were few p-c-Jun-positive cells in the Dox + SEMA3A-I group. Original magnification, ×400. p-c-Jun-positive cells/glomeruli was shown in the graph. *** p < 0.001.