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. 2020 Jun 8;21(11):4096. doi: 10.3390/ijms21114096

Figure 5.

Figure 5

(A) Chemokine signaling pathway. CCR2, CCR5, and CXCR3 belong to the group of G-protein coupled receptors (GPCRs). Schematic view of the components of the signaling pathway; see text for details. Components of the pathway that are increased in epilepsy are in blue. Therapeutic strategies to prevent the pathway are in red. (B) Lcn2/LCN2R signaling pathway. Schematic view of the components of the pathway. See text for details. Components of the pathway that are increased in epilepsy are in blue. Pointed arrows indicate direction of the signaling pathway. Blunt arrows indicate inhibition.