Decreased body weight and increased the percentages of liver weight to body weight in Erk2−/− (KO) livers. (a) The representative livers, liver histology (H&E, hematotoxylin and eosin staining), liver fibrosis (TRI, Trichrome staining) or immunostaining of α-SMA and ERK2 of the WT and Erk2−/− (KO) mice was under the chow diet (normal diet) treatment; (b) The liver weights (LW), body weight (BW), and the percentages of liver weight to body weight in Wild-type (WT) and Erk2−/− (KO) were represented as mean+/− SE under normal diet with tamoxifen injection. (WT, n = 9; KO, n = 8). (* p < 0.05).