Figure 4.
Effect of SYR on UVA-induced release of MMP-1 (A) and procollagen Iα1 (B) along with MMP-1 activation (C) in human dermal fibroblasts (HDFs). Cells were treated with given concentrations of SYR for 24 h after UVA irradiation (10 J/cm2), and the levels of MMP-1 and procollagen Iα1 release were measured by ELISA using cell culture medium. Retinoic acid was used as a positive control. Values are means ± SD of three independent experiment run in triplicate. Different letters (a–d) indicate statistically significant differences at the p < 0.05 level by Duncan’s multiple range test.