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. 2020 May 30;21(11):3943. doi: 10.3390/ijms21113943

Table 5.

Effect of mutated genes on human male fertility.

Mutated Genes Effects Ref
CLOCK polymorphism rs1801260 Normal seminal parameters [126]
CLOCK polymorphism rs3817444 Normal and abnormal seminal parameters [126]
CLOCK polymorphism rs1801260 TC genotype Lower motility compared to the TT genotype [127]
CLOCK polymorphism rs3749474 CC genotype Seminal volume reduction, lower concentration and sperm motility compared to TT genotype [127]