Table 4.
Urine 8-isoprostane concentrations by treatment, clock time and time point.
| Time Point | Spice, A.M. | Spice, P.M. | ||
|
Mean (SD)
pg/mg Cr |
Median (IQR)
pg/mg Cr |
Mean (SD)
pg/mg Cr |
Median (IQR)
pg/mg Cr |
|
| 0 h (baseline) | 1004.0 (400.0) | 968.6 (653.3) | 859.8 (307.9) | 903.6 (574.8) |
| 0–2 h | 917.7 (204.5) | 897.5 (370.9) | 976.2 (450.1) | 811.5 (781.5) |
| 2–4 h | 1390.7 (883.3) | 1119.1 (1596.8) | 1207.6 (495.7) | 1125.5 (939.4) |
| 4–6 h | 1096.5 (685.9) | 800.3 (1105.0) | 959.5 (333.6) | 879.2 (607.2) |
| No Spice, A.M. | No Spice, P.M. | |||
| 0 h (baseline) | 752.2 (225.3) | 800.5 (411.2) | 859.7 (220.1) | 838.2 (423.3) |
| 0–2 h | 863.4 (342.7) | 875.0 (658.1) | 893.4 (310.7) | 764.4 (509.7) |
| 2–4 h | 1020.4 (563.2) | 1053.1 (1056.7) | 1132.8 (675.7) | 971.0 (1222.0) |
| 4–6 h | 949.3 (413.2) | 968.3 (786.7) | 842.6 (337.9) | 785.5 (623.8) |
General linear models analysis, effect of treatment (spice vs. no spice), p = 0.02; clock time (A.M. vs. P.M.), p > 0.05; time point (hours 0, 0–2, 2–4, 4–6), p = 0.03. SD = standard deviation; IQR = Interquartile Range.