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Expression of CLDN4 in SSA/P-D.(A,B) Histopathological feature of SSA/P-D, (C–E) Protein expression of Ki-67 (C), p53 (B) and CLDN4 in the SSA/P-D lesion. Scale bar, 100 μm. (F,G) Subcellular localization of CLDN4 in SSA/P-D by western blot analysis. N, normal mucosa; TA, tubular adenoma; SSA/P, serrated sessile adenoma/polyp; SSA/P-D, SSA/P with dysplasia; M, membrane fraction; C, cytosolic fraction; N, nuclear fraction; Error bar, standard deviation from 3 independent trials.
