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. 2020 May 28;21(11):3840. doi: 10.3390/ijms21113840

Figure 5.

Figure 5

Effect of CPE on EMT phenotype in IEC6 cells and SSA/P-D. (A) Effect of CPE on protein levels of factors associated with EMT, stemness, and BRAF. (B) Effect of CPE pretreatment on cell growth. IEC6 cells were treated with CPE of IC5 for 24 h. (C) Effect of CPE on cell invasion. (D) Protein levels of nuclear YAP (nYAP), and factors associated with EMT or stemness were compared in normal mucosa (N), tubular adenoma (TA), SSA/P and SSA/P-D. Error bar, standard deviation from 3 independent trials. CPE, clostridium perfringens enterotoxin; EMT, epithelial-mesenchymal-transition.