. 2020 May 28;21(11):3840. doi: 10.3390/ijms21113840

Table 1.

EMT phenotype and YAP1 activation in SSA/P-D.

Tissue	n	E-Cadherin		P	CLDN4	Cytosol	P
Tissue	n	Retained	Decrease	P	Membrane	Cytosol	P
Normal	40	40	0		40	0
TA	28	28	0		28	0
SSA/P	25	25	0		25	0
SSA/P-D	12	2	10	<0.0001	3	9	<0.0001
Tissue	n	YAP1	Nuclear	P	TAZ	Nuclear	P
Tissue	n	Cytosol	Nuclear	P	Cytosol	Nuclear	P
Normal	40	40	0		40	0
TA	28	28	0		28	0
SSA/P	25	25	0		25	0
SSA/P-D	12	3	9	<0.0001	12	0	NS

(1) E-cadherin levels were compared with that in normal mucosa. When the level was less than half of that in normal mucosa, it was considered as a decrease. (2) Subcellular localization of the protein was determined by immune histochemistry. (3) P-value was calculated by chi-square test. Normal, normal mucosa; TA, tubular adenoma; SSA/P, serrated sessile adenoma/polyp; SSA/P-D, SSA/P with dysplasia.