Figure 6.

Distributions of the read (%) of amino acid sequences of CDR3 regions of TRAV and TRAJ in the mouse model of cross-reactive metal allergy. Amino acid sequences of CDR3 regions in the Ni-Pd and Cr-Pd groups at 7 days after the third challenge. T cells bearing Trav8d-1-Traj49 and Trav5-1-Traj37 occupied a high proportion of cells in the Ni-Pd and Cr-Pd groups. Shared T cells bearing the same TRAV, TRAJ, and CDR3 sequences colored in Figure 6 were obtained from both groups. Mucosal-associated invariant T (MAIT) cells and invariant natural killer T (iNKT) cells were also observed in both groups.