Table 2.
Characteristics of studies that included patients who underwent surgery for pancreatic with metachronous liver metastasis.
| Author | Time period | Patient number | Age | Female/male | No. of LM | Size of LM | Neoadjuvant therapy | Primary lesion | Operation for liver metastases | Mortality | Interval between pancreatectomy and LM | OS | Positive prognostic factors |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Zanini et al.20 | 2003–2014 | 4 | 48 (39–56) | 0/4 | 1 | 2.2 (1.8–3.5) | 0% | PD (55%) | Wedge resection (100%) | 0% | 9 | 11.4 | Metachronous, Single LM |
| Dünschede et al.6 | 1996–2008 | 4 | 42 (41–81) | 2/2 | 1.75 (1–2) | 2.2 (1–3) | NR | NR | Minor hepatectomy (100%) | 0% | 9 | 31 | NR |
| Hackert et al.7 | 2001–2014 | 23 | NR | NR | NR | NR | 23% | PD (43%) DP (41%) TP (17%) |
Minor hepatectomy (74%) Major hepatectomy (26%) |
4.3% | 18.4 | 14.8 | NR |
DP, distal pancreatectomy; LM, liver metastases; NR, not reported; OS, overall survival; PD, pancreatoduodenectomy; TP, total pancreatectomy.