Table 1.
Clinical characteristics of patients with and without seizures.
| Characteristics |
Any seizure |
Early seizure |
||||
|---|---|---|---|---|---|---|
| Yes (n = 193, 8.3%) | No (n = 2132, 91.7%) | p | Yes (n = 163, 7.0%) | No (n = 2162, 93%) | p | |
| Age, years, mean (SD) | 69.3 (13.3) | 68.9 (13.9) | 0.68 | 69.0 (13.3) | 68.9 (13.9) | 0.92 |
| Male sex, n (%) | 96 (49.7) | 1205 (56.5) | 0.069 | 85 (52.1) | 1216 (56.2) | 0.31 |
| Premorbid mRS, median [IQR] | 0 [0, 1] | 0 [0, 1] | 0.001 | 0 [0, 1] | 0 [0, 1] | 0.015 |
| Systolic blood pressure, mmHg, mean (SD) | 172.8 (30.8) | 175.0 (29.7) | 0.34 | 173.7 (31.0) | 174.9 (29.7) | 0.63 |
| Glasgow Coma Scale, median [IQR] | 14 [11, 15] | 15 [12, 15] | 0.001 | 14 [11, 15] | 15 [12, 15] | 0.004 |
| NIHSS, median [IQR] | 15 [8.5, 20] | 12 [6, 18] | 0.001 | 16 [8, 20] | 12 [6, 18] | 0.002 |
| Prior antiplatelet, n (%) | 58 (30.1) | 553 (26.0) | 0.22 | 51 (31.3) | 560 (25.9) | 0.13 |
| Previous stroke/TIA, n (%) | 42 (22.0) | 288 (13.6) | 0.002 | 35 (21.6) | 295(13.8) | 0.006 |
| Previous ICH, n (%) | 19 (9.9) | 107 (5.0) | 0.005 | 15 (9.3) | 111 (5.2) | 0.027 |
| Ischaemic heart disease, n (%) | 22 (10.8) | 181 (8.6) | 0.17 | 18 (11.1) | 185 (8.7) | 0.29 |
| Hypertension, n (%) | 111 (58.1) | 1310 (61.8) | 0.31 | 97 (59.9) | 1324 (61.6) | 0.66 |
| Diabetes mellitus, n (%) | 26 (13.5) | 286 (13.4) | 0.97 | 20 (12.3) | 292 (13.5) | 0.67 |
| Atrial fibrillation, n (%) | 6 (3.1) | 65 (3.1) | 0.95 | 6 (3.7) | 65 (3.0) | 0.62 |
| Onset-CT time, hours, mean (SD) | 2.4 (1.3) | 2.3 (1.3) | 0.15 | 2.4 (1.3) | 2.3 (1.3) | 0.40 |
| Tranexamic acid, n (%) | 91 (47.2) | 1070 (50.2) | 0.42 | 76 (46.6) | 1085 (50.2) | 0.38 |
ICH: intracerebral haemorrhage; IQR: interquartile range; mRS: modified Rankin Scale; NIHSS: National Institute of Health Stroke Scale; SD: standard deviation; TIA: transient ischaemic attack.
Chi-squared, Student’s t and Mann–Whitney U tests are used for comparisons of categorical variables (n, %), mean (SD) and median (IQR) respectively.