Table 4.

Incidence of seizures by treatment groups according to subgroups of treatment completion and estimated glomerular filtration rate.

		Any seizures ≤90 days
Subgroups	N	Tranexamic acid	Placebo	p
Treatment completiona
Full dose	2207	80 (7.3)	89 (8.0)	0.49
Less than full dose	100	8 (16.7)	13 (24.5)	0.33
eGFR (mL/min/1.73 m2)b
≥60	1857	73 (7.8)	83 (9.0)	0.34
30–59	280	10 (7.5)	13 (8.8)	0.69
<30	38	3 (13.6)	1 (6.3)	0.46

Data are number (%) and statistics are Chi-squared test.

^aTreatment not given at all in 15 patients; completion status was uncertain in 3 patients.

^bEstimated glomerular filtration rate (eGFR) not available in 150 patients.