Table 5.
Effects of early seizures on day 90 outcomes.
| Outcomes | Early seizure (n = 139, 85.3%) | No early seizure (n = 1962, 90.7%) | OR/MD (95% confidence interval) | p |
|---|---|---|---|---|
| Deatha | 38 (27.9) | 237 (12.2) | 3.26 (1.98, 5.39) | <0.001 |
| mRS >3a | 88 (64.7) | 947 (48.6) | 1.79 (1.12, 2.86) | 0.015 |
| Barthel Indexb | 42.6 (43.9) | 60.7 (41.1) | −11.8 (−17.1, −6.6) | <0.001 |
| EQ-5D HUSb | 0.26 (0.40) | 0.39 (0.40) | −0.08 (−0.14, −0.03) | 0.005 |
| TICS-mb | 10.6 (12.7) | 17.4 (11.5) | −3.0 (−4.9, −1.1) | 0.002 |
| ZDSb | 73.1 (31.4) | 59.1 (26.9) | 6.6 (1.7, 11.4) | 0.008 |
EQ-5D HUS: EuroQoL-5 Dimensions Health Utility Status; ICU: intensive care unit; mRS: modified Rankin Scale; TICS-m: modified Telephone Interview Cognitive Status; ZDS: Zung Depression Scale.
aBinary logistic regression (OR, odds ratio) and bmultiple linear regression (MD, mean difference) adjusted for age, sex, premorbid modified Rankin Scale, prior antiplatelet therapy, National Institute of Health Stroke Scale, systolic blood pressure, onset to CT <3 h, baseline haematoma volume, intraventricular haemorrhage and lobar location. Analysis limited to 2101 participants who survived beyond seven days.