Comparison of metabolic connectivity among four groups at fourth week (i.e., 3 weeks of EA/sham EA intervention) after BPAI. (A,E) Significantly increased metabolic connectivity was observed among the right DLT, right motor cortex, left motor cortex, and left somatosensory cortex in the EA group, compared with the sham EA group. (B,F) Significantly increased metabolic connectivity was observed among the dorsolateral thalamus and left somatosensory cortex in the EA group, compared with the model. (C,G) Significantly increased metabolic connectivity among the left caudate putamen and left somatosensory cortex, as well as decreased metabolic connectivity between the right motor cortex and left somatosensory cortex, left motor cortex, and left somatosensory cortex was observed in the sham EA group, compared with the model group. (D,H) Changes in metabolic connectivity in the whole brain after BPAI (*P < 0.05; #P < 0.001). Red line, increased metabolic connectivity; gray line, decreased metabolic connectivity. BPAI, brachial plexus avulsion injury; EA, electroacupuncture; SC, somatosensory cortex; DLT, dorsolateral thalamus; MC, motor cortex; CPu, caudate putamen.