Skip to main content
. Author manuscript; available in PMC: 2020 Jun 24.
Published in final edited form as: Eur Respir J. 2019 May 30;53(5):1801291. doi: 10.1183/13993003.01291-2018

Figure 5. MMP-12 expression in eosinophilic emphysematous airways.

Figure 5.

(A) EPX (B) MMP-12 expression in airways of n=40 patients with chronic airways disease (diagnosis of either asthma or COPD) classified based on eosinophilia. Mann Whitney Test . (C) Correlation of sputum MMP-12 with IL-13 (n=40). Spearman rank. (D) MMP-12 expression in airways of both asthma (n=16) and COPD (n=24), classified based on eosinophilia and (E) COPD samples only, classified with respect to eosinophilia and emphysema. Kruskal Wallis with Dunn’s multiple correction. (F) Correlation of sputum MMP-12 with FEV1 % predicted in n=24 COPD patients. Spearman rank. Each symbol represents individual patient data, and median is indicated for each subset. Figure 5D, grey open circle indicates asthmatic patient with evidence of airspace enlargement. P≤0.05 considered as significant.