Figure 2. Silencing circSLAMF6 impeded glycolysis of GC cells under hypoxia.

AGS and MKN-45 cells were transfected with si-NC or si-circSLAMF6 after treatment of hypoxia for 48 h. (A,B) CircSLAMF6 expression was measured by qRT-PCR. (C-F) Glucose consumption and lactate production were determined by the Glucose Assay Kit and Lactate Assay Kit, respectively. (G,H) HK2 protein expression was detected via Western blot. *P<0.05.