Table 4.

Summary of solicited local and systemic reactions in 14 days following vaccination with the 2009 pandemic A/H1N1 MF59-adjuvanted influenza vaccine administered together with or 1 month before the seasonal virosomal-adjuvanted influenza vaccination to kidney transplant recipients and healthy controls

Adverse events	Sequential vaccine administrations				Simultaneous vaccine administrations
	Pandemic alone		Seasonal alone		Pandemic + seasonal
	Transplant recipients	Healthy controls	Transplant recipients	Healthy controls	Transplant recipients	Healthy controls
	(n = 16)	(n = 16)	(n = 16)	(n = 16)	(n = 16)	(n = 16)
Local reactions, n (%)
Erythema	0 (0.0)	1 (6.3)	1 (6.3)	1 (6.3)	1 (6.3)	1 (6.3)
Swelling/induration	3 (18.8)	2 (12.5)	2 (12.5)	1 (6.3)	4 (25.0)	2 (12.5)
Pain	3 (18.8)	2 (12.5)	2 (12.5)	2 (12.5)	4 (25.0)	2 (12.5)
At least one local event	4 (25.0)	4 (25.0)	3 (18.8)	3 (18.8)	4 (25.0)	3 (18.8)
Systemic reactions, n (%)
Fever ≥ 38°C	1 (6.3)	1 (6.3)	0 (0.0)	1 (6.3)	1 (6.3)	1 (6.3)
Rhinitis	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)
Malaise	1 (6.3)	0 (0.0)	1 (6.3)	1 (6.3)	1 (6.3)	0 (0.0)
Sleepiness	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)
Changed eating habits	0 (0.0)	1 (6.3)	0 (0.0)	0 (0.0)	0 (0.0)	1 (6.3)
Vomiting	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)
Diarrhoea	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)
At least one systemic event	2 (12.5)	2 (12.5)	1 (6.3)	2 (12.5)	2 (12.5)	2 (12.5)
At least one local or systemic event	4 (25.0)	4 (25.0)	3 (18.8)	4 (25.0)	5 (31.3)	4 (25.0)
Required drugs for local or systemic events	2 (12.5)	1 (6.3)	1 (6.3)	1 (6.3)	3 (18.8)	2 (12.5)
Serious adverse events	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)

Percentages in parentheses. No significant differences between the transplant recipients and healthy controls.