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Effect on QTc and proarrhythmia of experimental pharmacological therapies for COVID-1936
| QTc prolongation | TdP risk | |
|---|---|---|
| Chloroquine37–40 | Moderate ↑ | Low risk of TdP |
| Hydroxychloroquine41 | Moderate ↑ | Low risk of TdP |
| Azithromycin42–48 | Moderate ↑ | Very low risk of TdP |
| Lopinavir/ritonavir37 | Moderate ↑ | Low risk of TdP |
| Tocilizumab49 | Mild ↑ or ↓ | NR |
| Fingolimod | Mild ↑ | NR |
| Remdesivir | NR | NR |
| Interferon alfacon-1 | NR | NR |
| Ribavirin | NR | NR |
| Methylprednisolone | NR | NR |
NR, not reported; TdP, torsade de pointes.
