Table 4.
Comparison between patients with transient versus persistent AKI
Characteristics of Patients | Transient AKI (n = 4) | Persistent AKI (n = 51) | P-value |
---|---|---|---|
SCr (µmol/L) at admission, mean ± SD) | 87 ± 27 | 116 ± 106 | 0.16 |
SCr (µmol/L) at AKI, mean ± SD) | 81 ± 36 | 147 ± 109 | 0.02 |
SCr (µmol/L) 48h after AKI, mean ± SD) | 69 ± 29 | 196 ± 226 | <0.001 |
|
|
|
0.14 |
AKI Stage 1, n (%) | 1/4 (25) | 20/51 (39) | 0.18 |
AKI Stage 2, n (%) | 3/4 (75) | 16/51 (31) | |
AKI Stage 3, n (%) | 0 | 15/51 (30) | |
Fluid balance 48 h after AKI (mL), mean ± SD | 6146 ± 2519 | 8767 ± 4429 | 0.36 |
Fluid balance 72 h after AKI (mL), mean ± SD | 8070 ± 3732 | 12 805 ± 6378 | 0.29 |
Minimum diuresis (mL/kg/h), mean ± SD | 0.6 ± 0.2 | 0.5 ± 0.3 | 0.67 |
Urinary Na+ (mmol/L), mean ± SD | 81 ± 75 | 53 ± 40 | 0.52 |
Urinary K+ (mmol/L), mean ± SD | 34 ± 22 | 44 ± 21 | 0.46 |
Urinary urea (mmol/L), mean ± SD | 291 ± 80 | 327 ± 164 | 0.69 |
Urinary osmolarity (mmol/L), mean ± SD | 637 ± 330 | 515 ± 182 | 0.52 |
FeNa+ (%), mean ± SD | 0.6 ± 0.7 | 0.6 ± 0.9 | 0.96 |
FeUrea (%), mean ± SD | 39 ± 11 | 33 ± 12 | 0.35 |
UNa+/UK+ ratio, mean ± SD | 2.3 ± 1.6 | 1.7 ± 2 | 0.54 |
Proteinuria/creatininuria (mg/mmol), median (IQR) | 124 (38–203) | 82 (54–140) | 0.62 |
Albuminuria/creatininuria (mg/mmol), median (IQR) | 6 (6–8) | 9 (5–32) | 0.31 |
Albuminuria/proteinuria (%), mean ± SD | 8 ± 6 | 23 ± 20 | 0.03 |
Haematuria, n (%) | 3/4 (75) | 35/51 (69) | 1 |
Leucocyturia, n (%) | 1/4 (25) | 24/51 (47) | 0.62 |
Glycosuria, n (%) | 0 (0) | 2/51 (4) | 1 |
RRT, n (%) | NR | 10/51 (20) | NA |
Date of RRT initiation, median (IQR) | NR | 8 (4–10) | NA |
Indication of RRT initiation, n (%) | NR | N = 10 | NA |
Anuria ≥72h | 7/10 (70) | ||
[K+] >6 mmol/L | 1/10 (10) | ||
pH <7.15 | 2/10 (20) | ||
Acute pulmonary oedema | 0 (0) | ||
Death, n (%) | 0 (0) | 2/51 (4) | 1 |
Fe, fractional excretion; K+, potassium; Na+, sodium; NA, not available; NR, not relevant; UNa+/K+ ratio, urinary sodium/potassium ratio.