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. 2020 Jun 6;13(3):354–361. doi: 10.1093/ckj/sfaa099

Table 4.

Comparison between patients with transient versus persistent AKI

Characteristics of Patients Transient AKI (n = 4) Persistent AKI (n = 51) P-value
SCr (µmol/L) at admission, mean ± SD) 87 ± 27 116 ± 106 0.16
SCr (µmol/L) at AKI, mean ± SD) 81 ± 36 147 ± 109 0.02
SCr (µmol/L) 48h after AKI, mean ± SD) 69 ± 29 196 ± 226 <0.001
  • Defined using SCr criteria, n (%)

  • Defined using diuresis criteria, n (%)

  • 1/4 (25)

  • 3/4 (75)

  • 46/51 (90)

  • 25/51 (49)

0.14
AKI Stage 1, n (%) 1/4 (25) 20/51 (39) 0.18
AKI Stage 2, n (%) 3/4 (75) 16/51 (31)
AKI Stage 3, n (%) 0 15/51 (30)
Fluid balance 48 h after AKI (mL), mean ± SD 6146 ± 2519 8767 ± 4429 0.36
Fluid balance 72 h after AKI (mL), mean ± SD 8070 ± 3732 12 805 ± 6378 0.29
Minimum diuresis (mL/kg/h), mean ± SD 0.6 ± 0.2 0.5 ± 0.3 0.67
Urinary Na+ (mmol/L), mean ± SD 81 ± 75 53 ± 40 0.52
Urinary K+ (mmol/L), mean ± SD 34 ± 22 44 ± 21 0.46
Urinary urea (mmol/L), mean ± SD 291 ± 80 327 ± 164 0.69
Urinary osmolarity (mmol/L), mean ± SD 637 ± 330 515 ± 182 0.52
FeNa+ (%), mean ± SD 0.6 ± 0.7 0.6 ± 0.9 0.96
FeUrea (%), mean ± SD 39 ± 11 33 ± 12 0.35
UNa+/UK+ ratio, mean ± SD 2.3 ± 1.6 1.7 ± 2 0.54
Proteinuria/creatininuria (mg/mmol), median (IQR) 124 (38–203) 82 (54–140) 0.62
Albuminuria/creatininuria (mg/mmol), median (IQR) 6 (6–8) 9 (5–32) 0.31
Albuminuria/proteinuria (%), mean ± SD 8 ± 6 23 ± 20 0.03
Haematuria, n (%) 3/4 (75) 35/51 (69) 1
Leucocyturia, n (%) 1/4 (25) 24/51 (47) 0.62
Glycosuria, n (%) 0 (0) 2/51 (4) 1
RRT, n (%) NR 10/51 (20) NA
Date of RRT initiation, median (IQR) NR 8 (4–10) NA
Indication of RRT initiation, n (%) NR N = 10 NA
 Anuria ≥72h 7/10 (70)
 [K+] >6 mmol/L 1/10 (10)
 pH <7.15 2/10 (20)
 Acute pulmonary oedema 0 (0)
Death, n (%)  0 (0)  2/51 (4) 1

Fe, fractional excretion; K+, potassium; Na+, sodium; NA, not available; NR, not relevant; UNa+/K+ ratio, urinary sodium/potassium ratio.