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. 2020 May 22;13(3):347–353. doi: 10.1093/ckj/sfaa088

FIGURE 2.

FIGURE 2

(A) Patient 1 (trichrome stain, ×400): a glomerulus with global collapse of the capillaries, associated with marked hyperplasia and swelling of overlying podocytes that contain cytoplasmic large vacuoles. (B) Patient 1 (PAS stain, ×400): swollen podocytes showing numerous PAS-positive cytoplasmic droplets. (C) Patient 2 (Jones methenamine silver stain, ×400): pronounced collapsing features, with vacuolated podocytes and capillary obliteration. (D) Patient 2 (trichrome stain, ×200): a glomerulus with a FSGS collapsing variant, together with acute tubular injury and a few tubules with cytoplasmic protein droplets (arrow).