Structural features of ligands used in this study. (a) Using the 20:4 aliphatic chain as a model, shown are the two structural domains that were varied systematically. Domain A is the head group that can be carboxyl, amide, or glycerol ester. Domain B is the alkyl group that was varied as 20:4, 18:1, or 16:0. (b) From left to right are comparisons of ligands with different Domain A (functional head groups). From top to bottom are comparisons of ligands with different Domain B (saturation and length of the alkyl chain)