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Ligand binding to IFABP involves unique residues that are not used for binding to LFABP. (a) Significant chemical shift perturbations (CSPs) are indicated with a dash for IFABP bound to the indicated ligand. Residues in this region of LFABP were not significantly perturbed. (b) Amino acids 66–70 of the co‐crystal of IFABP with palmitate (PDB 2IFB) are shown. Residues 69 and 70 are involved in binding fatty acid, and all five residues are involved in binding ECs
