Table 1.
Baseline Characteristics
| CCIS 0 (n = 2911) | CCIS 1–2 (n = 1112) | CCIS 3–4 (n = 288) | CCIS > 4 (n = 169) | Total (n = 4480) | |
|---|---|---|---|---|---|
| Male | 1326 (45.6) | 559 (50.3) | 149 (51.7) | 110 (65.1) | 2,144 (47.9) |
| Age [IQR] | 47 [35, 58] | 71 [56, 81] | 78 [67, 85] | 77 [69, 83] | 55 [41, 72] |
| CCIS [IQR] | 0 [0, 0] | 1 [1, 2] | 3 [3, 4] | 6 [5, 8] | 0 [0, 1] |
| Comorbidities, no. (%) | |||||
| Myocardial infarction | 0 (0.0) | 65 (5.8) | 40 (13.9) | 44 (26.0) | 149 (3.3) |
| Heart failure | 0 (0.0) | 77 (6.9) | 66 (22.9) | 55 (32.5) | 198 (4.4) |
| Cerebrovascular disease | 0 (0.0) | 171 (15.4) | 85 (29.5) | 50 (29.6) | 306 (6.8) |
| Peripheral vascular disease | 0 (0.0) | 63 (5.7) | 52 (18.1) | 45 (26.6) | 160 (3.6) |
| Diabetes with complications | 0 (0.0) | 38 (3.4) | 60 (20.8) | 62 (36.7) | 160 (3.6) |
| Diabetes | 0 (0.0) | 206 (18.5) | 102 (35.4) | 88 (52.1) | 396 (8.8) |
| Dementia | 0 (0.0) | 100 (9.0) | 36 (12.5) | 20 (11.8) | 156 (3.5) |
| Hemi- or paraplegia | 0 (0.0) | 10 (0.9) | 5 (1.7) | 6 (3.6) | 21 (0.5) |
| Rheumatic disease | 0 (0.0) | 71 (6.4) | 34 (11.8) | 13 (7.7) | 118 (2.6) |
| Peptic ulcer | 0 (0.0) | 24 (2.2) | 19 (6.6) | 18 (10.7) | 61 (1.4) |
| COPD | 0 (0.0) | 306 (27.5) | 93 (32.3) | 66 (39.1) | 465 (10.4) |
| Chronic renal disease | 0 (0.0) | 30 (2.7) | 57 (19.8) | 67 (39.6) | 154 (3.4) |
| Mild liver disease | 0 (0.0) | 35 (3.1) | 11 (3.8) | 16 (9.5) | 62 (1.4) |
| Severe liver disease | 0 (0.0) | 0 (0.0) | 8 (2.8) | 10 (5.9) | 18 (0.4) |
| Cancer | 0 (0.0) | 156 (14.0) | 106 (36.8) | 86 (50.9) | 348 (7.8) |
| Metastatic cancer | 0 (0.0) | 0 (0.0) | 0 (0.0) | 49 (29.0) | 49 (1.1) |
| HIV/AIDS | 0 (0.0) | 0 (0.0) | 0 (0.0) | * | * |
CCIS, Charlson comorbidity index score; COPD, chronic obstructive pulmonary disease; IQR, interquartile range. *Low number of observations, blanked to ensure patient anonymity