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(A and B) Schematic overview and timeline of retinal organoid generation. (C) Representative phase contrast images of hESC-derived aggregates. Aggregates are shown before D2-12 and after D24-90 organoid trisection. RDM, retinal differentiation medium. hESC, human embryonic stem cell. NR, neural retina. RPE, retinal pigment epithelium. Scale bars, 200 μm.
