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. 2020 May 20;6(21):eaaz8400. doi: 10.1126/sciadv.aaz8400

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Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 4 — (A) Representative in vivo CL images of Ce6-NPs and CRET-NPs in the presence of H₂O₂. (B) CL kinetic profiles of Ce6-NPs and CRET-NPs. (C) Time-dependent PA imaging of the tumor site after systemic administration of Ce6-NPs and CRET-NPs. (D) Quantification of PA intensities of Ce6-NPs and CRET-NPs. Error bars represent the SD (n = 3). *P < 0.0001, analyzed by one-way ANOVA. (E) 3D-rendered PA images of Ce6-NPs and CRET-NPs. (F) Color Doppler images (left) and PA images (right) of liver tissues by CRET-NPs.