Table 1.
Demographic and Clinical Features of Sri Lankan Subjects With Fever and Respiratory Symptoms Who Were Selected for RNA Sequencinga
| Etiologic Classification | ||||
|---|---|---|---|---|
| Viral | Bacterial | |||
| Characteristic | Dengue n = 22 | Influenza n = 36 | Leptospirosis n = 10 | Scrub Typhus n = 11 |
| Age (years) | 31.3 (22.7–51.1) | 37.4 (23.0–57.2) | 40.9 (34.5–43.3) | 37.3 (28.0–50.9) |
| Male | 9 (40.9%) | 22 (61.1%) | 8 (80.0%) | 4 (36.4%) |
| Days of fever at enrollment | 4 (3–6) | 3 (3–4.5) | 4 (2–6) | 7 (4–12) |
| Number respiratory symptoms | 1 (1–2) | 2 (1–2) | 2 (1–2) | 1 (1–2) |
| Rhinitis/congestion | 6 (27.3%) | 15 (42.9%) | 0 | 2 (18.2%) |
| Cough | 11 (50.0%) | 35 (100.0%) | 6 (60.0%) | 9 (81.8%) |
| Sore throat | 4 (18.2%) | 11 (30.6%) | 6 (60.0%) | 2 (18.2%) |
| Shortness of breath | 7 (31.8%) | 6 (16.7%) | 3 (30.0%) | 1 (9.1%) |
| Pain with breathing | 4 (18.2%) | 2 (5.6%) | 4 (40.0%) | 3 (27.3%) |
| Temperature at admission (°F) | 101.5 (99.0–102.0) | 101.4 (99.0–102.0) | 103.2 (102.0–104.0) | 100.0 (98.4–103.0) |
| WBC count × 109/L within 48 hours of admission | 4.0 (2.7–5.2) | 7.4 (6.7–10.2) | 7.8 (5.9–9.6) | 11.3 (5.9–14.0) |
| Platelet count × 109/L within 48 hours of admission | 135 (88–154) | 200 (163–268) | 141 (87–182) | 208 (142–257) |
| Neutrophil% at admission | 71.5 (56.0–80.9) | 74.7 (70.0–78.6) | 80.7 (77.2–86.4) | 76.7 (66.6–82.0) |
| Lymphocyte% at admission | 20.9 (12.6–37.0) | 18.2 (12.8–20.5) | 9.5 (7.2–11.4) | 15.6 (10.8–27.4) |
| Antibiotic use at enrollment | 8 (36.4%) | 25 (69.4%) | 8 (80.0%) | 5 (45.5%) |
| Abnormal chest x-ray (if performed) | 0 of 5 | 1 of 12 (8.3%) | 0 of 3 | 2 of 5 (40.0%) |
Abbreviations: RNA, ribonucleic acid; WBC, white blood cell.
aMedian (25%–75% interquartile range) or frequency (percentage), as appropriate, is listed.