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. 2020 Jun 24;10:10236. doi: 10.1038/s41598-020-66951-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation plots of SNPs in regions that showed significant correlation by TWAS. Figure shows plots of polymorphism periphery of eight genes (a. TNFSF15, b. ERV3-1, and c. ZNF713) that showed significant correlation by TWAS. Each dot indicates -log10(p-values) before (gray) and after (blue) adjustment by gene (green) that showed correlation. ERV3-1 and ZNF713 lose correlation after adjusting by genes showing correlation, although the correlation of TNFSF15 remains.