Table 8.
Orthologs of enzymes involved in auxin (IAA) biosynthetic pathways based on RAST annotation. The data is based on mapping of orthologs to tryptophan metabolic pathway using RAST annotation.
| Pathway | Reaction | Enzyme catalyzing the reaction | No of strains having ortholog | Remarks |
|---|---|---|---|---|
| Tryptophan →Indole 3-pyruvate | EC 2.6.1.99, 2.6.1.27, 1.4.3.2 | |||
| Indole 3-pyruvate | (Aminotransferase) | 0 | ||
| Indole 3- pyruvate→ | EC4.1.1.43, 4.1.1.74 (Indole | |||
| Indole 3- acetaldehyde | pyruvate decarboxylase) | 0 | ||
| Indole 3- acetaldehyde→ | EC 1.2.1.3, 1.2.3.7 (Indole 3- | |||
| Indole acetate | acetaldehyde dehydrogenase) | 12 | ||
| EC 4.1.1.28 (Trip | ||||
| Tryptophan →Tryptamine | decarboxylase) | 1 | Only in CAI-85 | |
| Tryptamine→ Indole 3- | EC 1.4.3.22, 1.4.3.4 | absent in CAI-140 | ||
| Tryptamine | acetaldehyde | (Amine/Tyramine oxidase) | 14 | & KAI-90 |
| Indole 3-acetaldehyde→ | EC 1.2.1.3, 1.2.3.7 (Indole 3- | |||
| Indole acetate | acetaldehyde dehydrogenase) | 16 | ||
| Tryptophan→ Indole 3- | EC 1.13.12.3 (Tryptophan | Present only in | ||
| Indole 3-acetamide | acetamide | mono-oxygenase) | 1 | KAI-90 |
| Indole 3- acetamide→ | Absent in largest | |||
| Indole acetate | EC 3.5.1.4 (IAM hydrolase) | 9 | clade |