Table 2.
The association between serum BCAAs and frailty score under different models stratified by LTL in the oldest-old subjects.
| LTL | Model 1 | Model 2 | |||||
|---|---|---|---|---|---|---|---|
| β* | 95%CI | P | β* | 95%CI | P | ||
| BCAAs | overall | −0.04 | −0.05, −0.02 | <0.001 | −0.03 | −0.04, −0.01 | <0.001 |
| short | −0.02 | −0.04, −0.01 | 0.074 | −0.02 | −0.04, −0.01 | 0.174 | |
| long | −0.05 | −0.08, −0.03 | <0.001 | −0.04 | −0.06, −0.02 | <0.001 | |
| Val | overall | −0.04 | −0.05, −0.02 | <0.001 | −0.02 | −0.04, −0.01 | 0.002 |
| short | −0.01 | −0.03, 0.01 | 0.283 | −0.01 | −0.03, 0.01 | 0.407 | |
| long | −0.05 | −0.07, −0.03 | <0.001 | −0.04 | −0.06, −0.02 | 0.001 | |
| Leu | overall | −0.04 | −0.06, −0.03 | <0.001 | −0.03 | −0.04, −0.01 | <0.001 |
| short | −0.03 | −0.05, −0.01 | 0.031 | −0.02 | −0.04, −0.01 | 0.118 | |
| long | −0.05 | −0.07, −0.03 | 0.000 | −0.04 | −0.06, −0.02 | 0.001 | |
| Ile | overall | −0.03 | −0.05, −0.02 | <0.001 | −0.03 | −0.04, −0.01 | <0.001 |
| short | −0.02 | −0.04, −0.01 | 0.057 | −0.02 | −0.04, 0.01 | 0.139 | |
| long | −0.04 | −0.06, −0.02 | <0.001 | −0.03 | −0.05, −0.02 | 0.002 | |
BCAAs, branched-chain amino acids; Val, valine; Leu, leucine; Ile, isoleucine; LTL, leukocyte telomere length; 95% CI: 95% confidence interval; BMI, body mass index. *β refers to the average change of frailty score by one standard deviation increasement in amino acids concentration.
Model 1: crude. Model 2: adjusted for age and BMI.