Table 2.

Univariate and multivariate analysis for relapse-free survival of colon cancer was performed in each clinical stage.

Stage	I		IIa				IIb		IIc		IIIa		IIIb				IIIc
Factors	Univariate analysis		Univariate analysis		Multivariate analysis		Univariate analysis		Univariate analysis		Univariate analysis		Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis
	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P
Age
75≥ /<75	0.97.	0.94	1.22	0.21	—	—	1.3	0.29	1.63	0.10	1.02	0.97	1.12	0.30	—	—	1.12	0.50
Gender
M/F	1.53	0.20	1.25	0.14	—	—	0.96	0.84	1.04	0.88	0.93	0.86	1.29	0.01	1.29	0.01	1.21	0.17	1.21	0.16
Histology
Diff/Undiff	0.94	0.95	6.26	0.0003	6.11	0.0004	1.51	0.34	0.88	0.78	0.61	0.53	1.11	0.60	—	—	0.95	0.76
Dissected LN
12 > /12≤	0.89	0.71	1.54	0.01	1.42	0.11	1.37	0.27	2.13	0.03	0.99	0.97	1.41	0.008	1.36	0.06	1.30	0.30
Adjuvant
Yes/No	6.25	0.002	1.01	0.98	—	—	1.39	0.19	0.80	0.53	0.82	0.62	0.94	0.55	—	—	0.92	0.57
TM-LVI
C/A	1.9×10−9	0.42	2.31	<0.0001	2.32	0.0001	1.80	0.08	1.79	0.14	0.98	0.19	2.84	<0.0001	2.84	<0.001	1.91	0.0004	1.94	0.0004
B/A	0.96		1.60		1.54		1.03		0.91		2.17		1.70		1.69		1.19		1.21
C/B	2.1×10-9		1.44		1.50		1.75		1.95		0.45		1.66		1.68		1.61		1.60

TM-LVI was an independent prognostic factor for relapse-free survival of colon cancer in stage IIa, IIIb, and IIIc.

M/F, Male/Female; Diff/Undiff, Differentiated/Undifferentiated; LN, Lymph node; RR, Risk ratio; Bold type, P < 0.05.