Table 5.

Univariate and multivariate analysis for disease specific survival of rectal cancer was performed in each clinical stage.

Stage	I				IIa				IIb				IIc		IIIa				IIIb				IIIc
Factors	Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis		Univariate analysis		Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis
	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P	RR	P
Age
75 ≥ /<75	3.02	0.007	2.68	0.02	2.52	0.0007	2.55	0.0006	1.14	0.81			0.78	0.73	1.90	0.28			1.69	0.01	1.30	0.23	1.59	0.13	1.28	0.43
Gender
M/F	1.61	0.19			1.50	0.10			0.56	0.17			1.74	0.23	3.17	0.02	2.57	0.07	1.09	0.58			1.19	0.39
Histology
Diff/Undiff	1.8×109	0.21			0.88	0.86			0.62	0.55			0.32	0.07	0.18	0.03	0.22	0.047	1.16	0.67			0.67	0.17	0.69	0.22
Dissected LN
12 > /12≤	2.27	0.04	2.05	0.07	1.49	0.15			2.86	0.044	2.73	0.06	3.07	0.08	1.15	0.86			1.83	0.006	1.67	0.03	1.24	0.54
Adjuvant
Yes/No	1.21	0.80			1.48	0.16			1.36	0.49			2.02	0.12	0.39	0.04	0.45	0.1	0.63	0.005	0.71	0.06	0.68	0.1	0.70	0.13
TM-LVI
C/A	2.34	0.004	1.94	0.01	3.69	<0.0001	3.75	<0.0001	4.55	0.0003	4.32	0.0004	2.20	0.35	7.25	0.007	5.10	0.037	3.26	<0.0001	3.16	<0.0001	1.52	0.01	1.52	0.01
B/A	3.40		3.12		1.94		1.92		0.69		0.67		1.49		2.39		2.00		1.75		1.72		0.73		0.74
C/B	0.69		0.62		1.90		1.95		6.57		6.46		1.47		3.04		2.54		1.86		1.84		2.07		2.06

TM-LVI was an independent prognostic factor for relapse-free survival of rectal cancer in stage I, IIa, IIb, IIIa, IIIb, and IIIc.

M/F, Male/Female; Diff/Undiff, Differentiated/Undifferentiated; LN, Lymph node; RR, Risk ratio; Bold type, P < 0.05.