Table 2.
Adjusted p values (FDR) for the comparison of the 12 markers investigated in the present study between the NAT population and the five continental populations (AFR, AMR, EAS, EUR, SAS), based on Fisher’s exact test.
| Gene | SNP, ID | Reference allele | Adjusted p value (FDR) for the NAT population versus: | ||||
|---|---|---|---|---|---|---|---|
| AFR | AMR | EAS | EUR | SAS | |||
| TPMT | rs1142345 | T | 1.48e−105 | 5.44e−87 | 8.46e−114 | 3.82e−111 | 3.07e−114 |
| TPMT | rs1800460 | C | 6.47e−158 | 5.74e−110 | 2.64e−146 | 2.24e−132 | 2.24e−140 |
| MTHFR | rs1801133 | G | 3.17e−88 | 1.58e−11 | 2.31e−33 | 8.71e−25 | 5.72e−75 |
| MTRR | rs1801394 | A | 4.35e−83 | 2.04e−57 | 2.69e−68 | 4.89e−26 | 1.22e−29 |
| MTHFD1 | rs2236225 | G | 8.00e−01 | 6.73e−25 | 1.45e−01 | 4.58e−14 | 3.78e−23 |
| GGH | rs1800909 | A | 2.69e−98 | 2.59e−67 | 3.86e−78 | 8.70e−66 | 5.40e−65 |
| GGH | rs3758149 | G | 9.35e−38 | 6.70e−22 | 6.57e−26 | 6.77e−18 | 1.96e−17 |
| ATIC | rs4673993 | T | 1.85e−20 | 1.00e+00 | 1.00e+00 | 1.00e+00 | 7.89e−06 |
| ATIC | rs2372536 | C | 1.80e−29 | 1.00e+00 | 1.00e+00 | 1.00e+00 | 6.31e−05 |
| SLCO1B1 | rs2306283 | A | 7.09e−54 | 1.89e−05 | 1.33e−39 | 3.26e−03 | 2.37e−11 |
| SLCO1B1 | rs4149056 | T | 6.09e−78 | 1.48e−30 | 5.85e−36 | 5.73e−32 | 7.22e−56 |
| CCND1 | rs9344 | G | 1.49e−65 | 1.39e−26 | 1.04e−05 | 3.65e−12 | 1.02e−09 |