TABLE 2.
Antimicrobial susceptibility and antibiotic resistance genes of 11 isolates of K. pneumoniae isolated from blood cultures from patients with bloodstream infections at a Chinese hospital. Carbapenem resistance genes are underlined.
| Isolate | Susceptible to: | Non-susceptible to: | Antibiotic resistance genes |
| KP29198 | MEM, GEN, AMK, CIP, LEV, TGC, POL, SXT | AMX, AMC, TZP, KZ, FEP, CRO, CXM, CAZ, FOX, MOX, ATM, IMP, FOS | blaKPC–2, blaCTX–M–3, blaSHV–36, aac(6’)Ib-cr, dfrA14, fosA, qnrS1, oqxA, oqxB, arr-3 |
| KP46050 | AMC, TZP, FEP, CRO, CXM, CAZ, FOX, MOX, ATM, IMP, MEM, GEN, AMK, CIP, LEV, TGC, FOS, POL, SXT | AMX, KZ | blaSHV–36, fosA, oqxA, oqxB |
| KP46748 | AMC, TZP, FEP, CRO, CXM, CAZ, FOX, MOX, ATM, IMP, MEM, GEN, AMK, CIP, LEV, TGC, FOS, POL, SXT | AMX, KZ | blaSHV–36, fosA, oqxA, oqxB |
| KP31319 | FEP, FOX, MOX, GEN, AMK, TGC, POL, SXT | AMX, AMC, TZP, KZ, CRO, CXM, CAZ, ATM, IMP, MEM, CIP, LEV, FOS | blaKPC–2, blaSHV–1, dfrA14, fosA, qnrS1, oqxA, oqxB |
| KP48273 | GEN, AMK, FOS, POL, | AMX, AMC, TZP, KZ, FEP, CRO, CXM, CAZ, FOX, MOX, ATM, IMP, MEM, CIP, LEV, TGC, SXT | blaKPC–2, blaSHV–1, dfrA14, fosA, qnrS1, oqxA, oqxB |
| KP46615 | AMC, TZP, KZ, FEP, CRO, CXM, CAZ, FOX, MOX, ATM, IMP, MEM, GEN, AMK, CIP, LEV, TGC, FOS, POL | AMX, SXT | blaSHV–1, fosA, oqxA, oqxB |
| KP48359 | AMC, TZP, KZ, FEP, CRO, CXM, CAZ, FOX, MOX, ATM, IMP, MEM, GEN, AMK, CIP, LEV, TGC, FOS, POL, SXT | AMX | blaSHV–11, fosA, oqxA |
| KP42223 | MOX, MEM, GEN, AMK, CIP, LEV, TGC, FOS, POL, SXT | AMX, AMC, TZP, KZ, FEP, CRO, CXM, CAZ, FOX, ATM, IMP | blaKPC–2, blaSHV–11, fosA, oqxA, oqxB |
| KP47507 | AMC, TZP, KZ, FEP, CRO, CXM, CAZ, FOX, MOX, ATM, IMP, MEM, GEN, AMK, CIP, LEV, POL, SXT | AMX, TGC, FOS | blaSHV–11, fosA, oqxA, oqxB |
| KP42388 | TGC, POL | AMX, AMC, TZP, KZ, FEP, CRO, CXM, CAZ, FOX, MOX, ATM, IMP, MEM, GEN, AMK, CIP, LEV, FOS, SXT | blaKPC–2, blaDHA–1, armA, sulI, mph(A), msr(E) |
| KP39929 | GEN, AMK, TGC, POL | AMX, AMC, TZP, KZ, FEP, CRO, CXM, CAZ, FOX, MOX, ATM, IMP, MEM, CIP, LEV, FOS, SXT | blaKPC–2 |
AMX: amoxicillin; AMC: amoxicillin-clavulanic acid; TZP: piperacillin-tazobactam; KZ: cefazolin; FEP: cefepime; CRO: ceftriaxone; CXM: cefuroxime; CAZ: ceftazidime; FOX: cefoxitin; MOX: moxalactam; ATM: aztreonam; IMP: imipenem; MEM: meropenem; GEN: gentamicin; AMK: amikacin; CIP: ciprofloxacin; LEV: levofloxacin; TGC: tigecycline; FOS: fosfomycin; POL: polymyxin B; SXT: trimethoprim-sulfamethoxazole.