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. 2020 Jun 18;13:84. doi: 10.3389/fnmol.2020.00084

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Copyright © 2020 El-Ghaiesh, Bahr, Ibrahiem, Ghorab, Alomar, Farag and Zaitone.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of metformin on striatal levels of c-caspase 3 and VEGF proteins. (A) Western blotting of c-caspase 3 and VEGF versus β-actin done using samples from brain striata. (B,C) Graphs present the densitometric analysis of western blotting of c-caspase 3 and VEGF. Data are mean ± SD for densitometric analysis of each gene relative to β-actin. Analysis was performed by applying one-way ANOVA followed by Bonferroni’s test. #: Different from vehicle group, $: Different from rotenone group. *: Different from rotenone + MTF 100 mg/kg group at p < 0.05 (n = 3).