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. 2020 Jun 18;10:716. doi: 10.3389/fonc.2020.00716

Table 2.

The characteristics of CRLM patients in early and advanced T classification.

Risk Factors N (%) T1/2 classificationa
n (%)
T3/4 classificationa
n (%)
Pb
Total 5,618 591(10.52) 5,027(89.48)
Age 0.628
  ≤ 60 yrs 2,932(52.19) 306(51.78) 2,626(52.24)
 >60 yrs 2,686(47.81) 285(48.22) 2,401(47.76)
Gender 0.158
 Female 2,281(40.60) 224(37.90) 2,057(40.92)
 Male 3,227(59.40) 367(61.10) 2,970(59.08)
Race 0.246
 White 4,198(74.72) 425(7.91) 3,733(74.05)
 Black 874(15.56) 101(17.09) 773(15.38)
 Other 546(9.72) 65(11.00) 481(9.57)
Marriage
 Married 3,196(56.89) 321(54.31) 2,875(57.19) 0.425
 Divorced 1,054(18.76) 110(18.61) 944(18.78)
 Single 1,114(19.83) 130(22.00) 984(19.57)
 Unknown 254(4.52) 38(5.88) 224(4.46)
Location 0.000
 Colon 4,650(82.77) 409(69.20) 4,650(82.77)
 Rectum 968(17.23) 182(30.80) 968(17.23)
 Histology 0.001
 Adenocarcinoma 5,285(94.07) 575(97.29) 4,710(93.69)
 Mucinous adenocarcinoma 316(5.62) 14(2.37) 302(6.01)
 Signet ring cell carcinoma 17(0.30) 2(0.34) 15(0.30)
Differential grade 0.000
 Well 227(4.84) 42(7.11) 185(3.68)
 Moderate 4,131(73.53) 471(79.70) 3,660(75.44)
 Poor/Undifferentiated 1,260(22.43) 78(13.20) 1,182 (23.51)
N-classification 0.000
 N0 1,331(23.69) 349(59.05) 982(20.02)
 N1 2,252(40.09) 203(34.35) 2,049(40.76)
 N2 2,035(36.22) 39(6.60) 1,996(39.71)
CEA c 0.000
 Negative 784(13.96) 59(9.98) 725(14.42)
 Positive 3,336(59.38) 394(66.67) 2,942(58.52)
 Unknown 1,498(26.66) 138(23.35) 1,360(27.05)

CRLM, metastatic liver colorectal cancer; CEA, carcinoembryonic antigen.

a

T classification was classified as T1, T2, T3, T4 subgroups and N classification was classified as N0, N1, N2 according to the 7th AJCC TNM staging system.

b

P values were calculated using Chi-Squared tests.

c

The reference value of CEA : nonsmoker <2.5ng/ml; smoker <5ng/ml.