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. 2020 Jun 18;11:539. doi: 10.3389/fphys.2020.00539

Figure 3.

Figure 3

JMJD1C regulates protein synthesis in cardiomyocytes. (A) JMJD1C knockdown reduces Ang II-induced protein synthesis. **p < 0.01 vs. Ad-shCtrl+PBS; ##p < 0.01 vs. Ad-shCtrl+Ang II. n = 3 in each group. (B) JMJD1C overexpression promotes Ang II-induced protein synthesis. **p < 0.01 vs. Ad-Ctrl+PBS; ##p < 0.01 vs. Ad-Ctrl+Ang II. n = 3 in each group. (C) JMJD1C knockdown reduces phosphorylation of p70S6K1 and eEF2 in Ang II-treated cardiomyocytes. **p < 0.01 vs. Ad-shCtrl. n = 3 in each group. (D) JMJD1C overexpression increases phosphorylation of p70S6K1 and eEF2 in Ang II-treated cardiomyocytes. **p < 0.01 vs. Ad-Ctrl. n = 3 in each group.