TABLE 3.
Prevalence of clinical findings and association of clinical findings with urogenital M. genitalium infectiona
| Clinical finding |
M. genitalium infection prevalence |
|||
|---|---|---|---|---|
| Female (n = 1,737) |
Male (n = 1,563) |
|||
| n/N (%) | ORb (95% CI) | n/N (%) | ORb (95% CI) | |
| Clinician-reported urogenital signsc | ||||
| Any sign of urogenital infection | 115/1,034 (11.1) | 1.32 (0.95, 1.83) | 77/608 (12.7) | 1.43 (1.03, 1.98) |
| Swollen lymph nodes in groin | 0 | NC | 11/45 (24.4) | 2.87 (1.42, 5.77) |
| Genital blisters/sores/bumps/rash/warts | 12/45 (26.7) | 3.39 (1.72, 6.69) | 11/135 (8.1) | 0.73 (0.39, 1.39) |
| Abnormal vaginal odor | 51/361 (14.1) | 1.65 (1.16, 2.33) | ||
| Abnormal vaginal discharge | 98/858 (11.4) | 1.32 (0.97, 1.81) | ||
| Clear | 6/58 (10.3) | Reference | ||
| White | 58/536 (10.8) | 1.05 (0.43, 3.13)d | ||
| Pink, bloody, brown, gray, other | 18/156 (11.5) | 1.13 (0.40, 3.67)d | ||
| Yellow, green (pus-like) | 16/108 (14.8) | 1.51 (0.52, 4.99)d | ||
| Urethral erythema | 0 | NC | 17/207 (8.2) | 0.73 (0.43, 1.23) |
| Abnormal urethral discharge | 1/16 (6.3) | 0.59 (0.01, 3.87) | 46/244 (18.9) | 2.34 (1.61, 3.40) |
| Lower abdominal/pelvic tenderness | 1/35 (2.9) | 0.26 (0.01, 1.55) | 1/5 (20.0) | 2.13 (0.04, 21.63) |
| Pain or swelling of testicles | 3/25 (12.0) | 1.16 (0.22, 3.92) | ||
| Clinician's diagnosisc | ||||
| Any clinical finding | 122/1,024 (11.9) | 1.65 (1.18, 2.31) | 103/755 (13.6) | 1.90 (1.36, 2.65) |
| Cervicitis | 9/66 (13.6) | 1.42 (0.61, 2.96) | ||
| Pelvic inflammatory disease | 2/11 (18.2) | 1.98 (0.21, 9.68) | ||
| Vaginitis | 101/752 (13.4) | 1.88 (1.37, 2.58) | ||
| Cystitis | 1/13 (7.7) | 0.74 (0.02, 5.04) | 1/9 (11.1) | 1.06 (0.02, 7.99) |
| Urethritis | 0/2 (0.0) | NC | 83/438 (18.9) | 2.97 (2.14, 4.13) |
| Abdominal/pelvic pain | 2/17 (11.8) | 1.18 (0.13, 5.16) | 0 | NC |
| Genital lesions | 0/4 (0.0) | NC | 1/12 (8.3) | 0.77 (0.02, 5.35) |
| Genital warts | 1/2 (50.0) | 8.91 (0.11, 700.16) | 4/31 (12.9) | 1.26 (0.32, 3.69) |
| Urinary tract infection | 0/16 (0.0) | NC | 0 | NC |
| HSV | 3/13 (23.1) | 2.69 (0.47, 10.57) | 0/9 (0.0) | NC |
| Other,e not available, unknown | 13/186 (7.0) | 0.64 (0.36, 1.15) | 15/264(5.7) | 0.46 (0.27, 0.80) |
a
HSV, herpes simplex virus infection; n/N, number of patients with urogenital M. genitalium infection/total number of patients with the indicated clinical finding; NC, not calculable.
b
Unless otherwise noted, the referent category is the absence of the sign or diagnosis.
c
The clinician could report multiple signs or diagnoses.
d
The referent is clear abnormal vaginal discharge.
e
Includes balanitis, proctitis, and lymphadenopathy.