TABLE 4.
Characteristics associated with asymptomatic urogenital M. genitalium infectiona
| Characteristic |
M. genitalium infection prevalence |
|||||
|---|---|---|---|---|---|---|
| Females |
Males |
|||||
| % (n/N) |
ORc (95% CI) | % (n/N) |
ORc (95% CI) | |||
| Symb (n = 1,053) | ASymb (n = 684) | Symb (n = 866) | ASymb (n = 697) | |||
| Age (yr) | ||||||
| 15–24 | 21.4 (65/304) | 16.4 (23/140) | 1.38 (0.82, 2.34) | 18.8 (30/160) | 13.6 (17/125) | 1.47 (0.77, 2.80) |
| 25–34 | 10.2 (46/452) | 7.4 (22/299) | 1.43 (0.84, 2.42) | 14.9 (46/309) | 10.3 (28/271) | 1.52 (0.92, 2.51) |
| 35–49 | 4.0 (10/247) | 5.6 (9/160) | 0.71 (0.25, 2.02) | 11.7 (25/213) | 6.6 (12/181) | 1.87 (0.91, 3.84) |
| ≥50 | 2.0 (1/50) | 0.0 (0/85) | Inf (0.09, Inf) | 1.6 (3/184) | 3.3 (4/120) | 0.48 (0.07, 2.90) |
| Raced | ||||||
| White | 7.4 (23/310) | 6.0 (17/281) | 1.24 (0.65, 2.38) | 8.5 (22/259) | 5.3 (15/281) | 1.65 (0.83, 3.25) |
| Black | 13.6 (92/677) | 9.2 (35/382) | 1.56 (1.03, 2.35) | 13.9 (81/584) | 11.5 (44/382) | 1.24 (0.84, 1.83) |
| Asian | 23.8 (5/21) | 0.0 (0/8) | Inf (0.49, Inf) | 0.0 (0/9) | 0.0 (0/9) | NC |
| Unknown/other race | 7.0 (4/57) | 9.1 (2/22) | 0.75 (0.10, 8.99) | 11.5 (3/26) | 7.3 (3/41) | 1.65 (0.20, 13.30) |
| Ethnicitye | ||||||
| Hispanic | 6.7 (14/210) | 5.3 (9/171) | 1.29 (0.50, 3.46) | 7.3 (12/164) | 6.3 (11/175) | 1.18 (0.50, 2.75) |
| Non-Hispanic | 12.6 (106/838) | 8.8 (45/509) | 1.49 (1.03, 2.16) | 13.0 (90/694) | 9.7 (50/515) | 1.39 (0.96, 2.00) |
| Collection site (region)f | ||||||
| Mid-Atlantic | 13.2 (9/68) | 9.5 (7/74) | 1.46 (0.45, 4.91) | 11.7 (9/77) | 9.8 (4/41) | 1.22 (0.31, 5.81) |
| Midwest | 12.1 (17/141) | 12.2 (6/49) | 0.98 (0.34, 3.24) | 13.2 (7/53) | 15.6 (7/45) | 0.83 (0.23, 3.04) |
| Northeast | 12.7 (9/71) | 11.4 (4/35) | 1.13 (0.29, 5.39) | 12.9 (4/31) | 8.0 (7/88) | 1.71 (0.34, 7.34) |
| Northwest | 0.0 (0/9) | 0.0 (0/3) | NC | 6.4 (3/47) | 0.0 (0/6) | Inf (0.07, Inf) |
| Southeast | 11.8 (54/459) | 7.4 (18/244) | 1.67 (0.96, 2.92) | 12.1 (60/494) | 10.6 (24/227) | 1.17 (0.71, 1.93) |
| Southwest | 10.8 (33/305) | 6.8 (19/279) | 1.66 (0.92, 2.99) | 12.8 (21/164) | 6.6 (19/290) | 2.09 (1.09, 4.02) |
| Collection site (type) | ||||||
| Clinical research center | 6.6 (19/287) | 7.1 (24/338) | 0.93 (0.50, 1.73) | 6.0 (23/383) | 6.9 (20/288) | 0.86 (0.46, 1.59) |
| Emergency medicine clinic | 15.2 (7/46) | 50.0 (1/2) | 0.18 (0.00, 16.09) | 15.2 (7/46) | 0.0 (0/7) | Inf (0.27, Inf) |
| Family medicine/OB-GYN clinic | 0.0 (0/5) | 6.3 (1/16) | NC | NC | NC | NC |
| Family planning clinic | 13.0 (31/238) | 5.7 (8/140) | 2.47 (1.07, 6.40) | 16.3 (15/92) | 9.3 (13/140) | 1.90 (0.86, 4.21) |
| Hospital system high-risk STI clinic | 13.7 (62/452) | 10.8 (16/148) | 1.31 (0.73, 2.35) | 17.6 (51/289) | 14.9 (22/148) | 1.23 (0.71, 2.12) |
| Public health clinic | 12.0 (3/25) | 10.0 (4/40) | 1.23 (0.16, 7.99) | 14.3 (8/56) | 5.3 (6/114) | 3.00 (0.85, 11.03) |
Asym, asymptomatic; Inf, infinity; n/N, number of patients with urogenital M. genitalium infection/total number of patients with the indicated characteristic; NC, not calculable; Sym, symptomatic.
Symptom status is determined based on patient-reported symptoms.
Odds ratio represents the association of M. genitalium with symptoms in each subgroup. The referent category in all cases is asymptomatic participants.
Participants could report multiple responses.
Ethnicity was self-reported as unknown by 5 female and 8 male participants.
Mid-Atlantic: Maryland, North Carolina, and Washington, DC. Midwest: Indiana, Michigan, Nebraska, and Ohio (2 sites). Northeast: Connecticut and New Jersey. Northwest: Washington. Southeast: Alabama, Georgia, Florida (3 sites), and Louisiana. Southwest: California (2 sites) and Texas (2 sites).