TABLE 8.
BioFire PN panel semiquantitative concordance with qRefCx
| Target | Specimen | No. of samples with result/total (%) for qRefCx range (CFU/ml) [BioFire PN panel equivalent bin]a
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 103.5 to <104 [104] |
104 to <105 [104 or 105] |
105 to <106 [105 or 106] |
106 to <107 [106 or ≥107] |
≥107 [≥107] |
||||||||||
| ND | = | > | < | = | > | < | = | > | < | = | < | = | ||
| A. calcoaceticus-A. baumannii complex | BAL | 0/0 () | 0/0 () | 0/0 () | 0/0 () | 0/0 () | ||||||||
| SPU | 1/5 (20.0) | 4 | 1/1 (100) | 1 | 0/2 (0) | 1 | 3/3 (100) | 0/0 () | ||||||
| E. cloacae complex | BAL | 0/1 (0) | 1 | 1 | 1/7 (14.3) | 5 | 0/3 (0) | 3 | 0/0 () | 1/1 (100) | ||||
| SPU | 0/1 (0) | 1 | 1 | 3/6 (50.0) | 2 | 1/3 (33.3) | 2 | 1/1 (100) | 1/1 (100) | |||||
| E. coli | BAL | 0/4 (0) | 4 | 1/7 (14.3) | 6 | 0/0 () | 0/0 () | 1/1 (100) | ||||||
| SPU | 2/3 (66.7) | 1 | 1 | 1/13 (7.7) | 11 | 2/5 (40.0) | 3 | 1/1 (100) | 2/2 (100) | |||||
| H. influenzae | BAL | 0/2 (0) | 2 | 0/2 (0) | 2 | 0/5 (0) | 5 | 0/0 () | 1/1 (100) | |||||
| SPU | 0/0 () | 1 | 0/12 (0) | 11 | 1 | 1/4 (25.0) | 2 | 2/2 (100) | 0/0 () | |||||
| K. aerogenes | BAL | 0/1 (0) | 1 | 1 | 1/2 (50.0) | 0/1 (0) | 1 | 1 | 2/3 (66.7) | 0/0 () | ||||
| SPU | 1/1 (100) | 1 | 0/1 (0) | 0/1 (0) | 1 | 1/1 (100) | 0/0 () | |||||||
| K. oxytoca | BAL | 0/0 () | 1/2 (50.0) | 1 | 0/0 () | 0/0 () | 0/0 () | |||||||
| SPU | 1/3 (33.3) | 2 | 0/3 (0) | 3 | 2/2 (100) | 1/1 (100) | 0/0 () | |||||||
| K. pneumoniae group | BAL | 0/5 (0) | 5 | 3/5 (60.0) | 2 | 0/0 () | 2/2 (100) | 3/3 (100) | ||||||
| SPU | 1 | 3/6 (50.0) | 2 | 2/7 (28.6) | 5 | 5/7 (71.4) | 2 | 2/2 (100) | 1 | 0/1 (0) | ||||
| M. catarrhalis | BAL | 0/0 () | 0/0 () | 0/0 () | 0/0 () | 0/0 () | ||||||||
| SPU | 0/1 (0) | 1 | 0/1 (0) | 1 | 0/1 (0) | 1 | 1/1 (100) | 1/1 (100) | ||||||
| Proteus spp. | BAL | 0/1 (0) | 1 | 1/1 (100) | 0/1 (0) | 1 | 1/1 (100) | 1/1 (100) | ||||||
| SPU | 0/1 (0) | 1 | 5/10 (50.0) | 5 | 2/3 (66.7) | 1 | 1/1 (100) | 0/0 () | ||||||
| P. aeruginosa | BAL | 0/4 (0) | 4 | 2/15 (13.3) | 13 | 1/13 (7.7) | 12 | 2/2 (100) | 2/2 (100) | |||||
| SPU | 2 | 3/15 (20.0) | 10 | 1 | 7/42 (16.7) | 34 | 5/24 (20.8) | 19 | 19/19 (100) | 6/6 (100) | ||||
| S. marcescens | BAL | 0/1 (0) | 1 | 1/4 (25.0) | 3 | 0/1 (0) | 1 | 0/0 () | 0/0 () | |||||
| SPU | 0/4 (0) | 4 | 1 | 4/12 (33.3) | 7 | 3/6 (50.0) | 3 | 4/4 (100) | 1/1 (100) | |||||
| S. aureus | BAL | 1 | 0/11 (0) | 10 | 0/19 (0) | 19 | 1/9 (11.1) | 8 | 5/5 (100) | 3/3 (100) | ||||
| SPU | 1 | 1/18 (5.6) | 16 | 11/45 (24.4) | 34 | 13/28 (46.4) | 15 | 1 | 12/13 (92.3) | 1 | 7/8 (87.5) | |||
| S. agalactiae | BAL | 0/0 () | 0/1 (0) | 1 | 0/0 () | 0/0 () | 0/0 () | |||||||
| SPU | 0/3 (0) | 3 | 1/5 (20.0) | 4 | 0/1 (0) | 1 | 0/0 () | 0/0 () | ||||||
| S. pneumoniae | BAL | 1/2 (50.0) | 1 | 1/2 (50.0) | 1 | 0/1 (0) | 1 | 0/0 () | 0/0 () | |||||
| SPU | 2/3 (66.7) | 1 | 2/6 (33.3) | 4 | 0/2 (0) | 2 | 4/4 (100) | 1/1 (100) | ||||||
| S. pyogenes | BAL | 0/0 () | 2/2 (100) | 0/0 () | 0/0 () | 0/0 () | ||||||||
| SPU | 0/0 () | 0/3 (0) | 3 | 1/1 (100) | 1/1 (100) | 1/1 (100) | ||||||||
| Overall | BAL | 1/32 (3.1) | 1/32 (3.1) | 30/32 (93.8) | 2/69 (2.9) | 14/69 (20.3) | 53/69 (76.8) | 0/34 (0) | 2/32 (5.9) | 32/34 (94.1) | 1/13 (7.7) | 12/13 (92.3) | 0/12 (0) | 12/12 (100) |
| SPU | 4/64 (6.2) | 14/64 (21.9) | 46/64 (71.9) | 6/167 (3.6) | 37/167 (22.2) | 124/167 (74.3) | 2/90 (2.2) | 35/90 (38.9) | 53/90 (58.9) | 1/54 (1.9) | 53/54 (98.1) | 2/22 (6.1) | 20/22 (90.9) | |
a
Concordance is indicated as follows: ND, not detected by BioFire PN panel; <, detected by the PN panel but reported in a lower bin not concordant with qRefCx (or not detected); =, detected by the PN panel in a bin concordant with qRefCx; >, detected by the PN panel but reported in a higher bin not concordant with qRefCx.