TABLE 3.

Composite reference method versus NG-Test Carba 5 results by isolate tested from blood or MacConkey agar, post-discrepant analysis^a

Organism (total no. of isolates)	NG-Test Carba 5 carbapenemase target (no. of expected positives)	No. of results				PPA	95% CI		NPA	95% CI
		TP	FP	FN	TN		Low	High		Low	High
Enterobacterales (240)	KPC (n = 83)	83	0	0	157	100.0	95.6	100.0	100.0	97.6	100.0
	OXA-48-like (n = 17)	17	0	0	223	100.0	81.6	100.0	100.0	98.3	100.0
	VIM (n = 10)	10	0	0	230	100.0	72.3	100.0	100.0	98.4	100.0
	IMP (n = 7)	7	0	0	233	100.0	64.6	100.0	100.0	98.4	100.0
	NDM (n = 35)	35	0	0	205	100.0	90.1	100.0	100.0	98.2	100.0
	OXA-48 + NDM (n = 2)	2	0	0	238	100.0	34.2	100.0	100.0	98.4	100.0
	OXA-48 + VIM (n = 1)	1	0	0	239	100.0	20.7	100.0	100.0	98.4	100.0
	KPC + NDM (n = 1)	1	0	0	239	100.0	20.7	100.0	100.0	98.4	100.0
	Overall (n = 156)	156	0	0	84	100.0	97.6	100.0	100.0	95.6	100.0
Pseudomonas aeruginosa (69)	KPC (n = 2)	2	0	0	67	100.0	34.2	100.0	100.0	94.6	100.0
	OXA-48-like (n = 0)	0	0	0	69	NA	NA	NA	100.0	94.7	100.0
	VIM (n = 9)	9	0	0	60	100.0	70.1	100.0	100.0	94.0	100.0
	IMP (n = 5)	5	0	0	64	100.0	56.6	100.0	100.0	94.3	100.0
	NDM (n = 0)	0	0	0	69	NA	NA	NA	100.0	94.7	100.0
	Overall (n = 16)	16	0	0	53	100.0	80.6	100.0	100.0	93.2	100.0
Enterobacterales+ P. aeruginosa (309)	Overall (n = 172)	172	0	0	137	100.0	97.8	100.0	100.0	97.3	100.0

^aThe results on blood and MacConkey agars were the same. Testing was performed at sites 1 to 3. TP, true positive; FP, false positive; TN, true negative; FN, false negative; NA, not applicable; 95% CI, 95% confidence interval.